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Article

A role for phosphatidic acid in the formation of "supersized" lipid droplets.

PLoS genetics - 1 Jul 2011

Fei Weihua, Shui Guanghou, Zhang Yuxi, Krahmer Natalie, Ferguson Charles, Kapterian Tamar S, Lin Ruby C, Dawes Ian W, Brown Andrew J, Li Peng, Huang Xun, Parton Robert G, Wenk Markus R, Walther Tobias C, Yang Hongyuan

Abstract excerpt

Lipid droplets (LDs) are important cellular organelles that govern the storage and turnover of lipids. Little is known about how the size of LDs is controlled, although LDs of diverse sizes have been observed in different tissues and under different (patho)physiological conditions. Recent studies have indicated that the size of LDs may influence adipogenesis, the rate of lipolysis and the oxidation of fatty...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21829381
DOI: 10.1371/journal.pgen.1002201
PMCID: PMC3145623

Genes

CDS1
MRPS35

Provenance

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