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Article

Reciprocal Transcriptional Regulation of Metabolic and Signaling Pathways Correlates With Disease Severity in Heart Failure

10 Aug 2011

Abstract excerpt

BACKGROUND: Systolic heart failure (HF) is a complex systemic syndrome that can result from a wide variety of clinical conditions and gene mutations. Despite phenotypic similarities, characterized by ventricular dilatation and reduced contractility, the extent of common and divergent gene expression between different forms of HF remains a matter of intense debate. METHODS AND RESULTS: Using a meta-analysis of 28...

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Share to Cardiac Fibrosis and Remodeling
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PMID: 21828333
DOI: 10.1161/circgenetics.110.957571

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