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Article

Growth factor signalling in the regulation of <i>α</i> ‐cell fate

8 Aug 2011

Abstract excerpt

Glucagon plays critical roles in regulating glucose homeostasis, mainly by counteracting the effects of insulin. Consequently, the dysregulated glucagon secretion that is evident in type 2 diabetes has significant implications in the pathophysiology of the disease. Glucagon secretion from pancreatic α-cells has been suggested to be modulated by blood glucose, signals from the nervous system and endocrine...

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Identifiers

PMID: 21824253
DOI: 10.1111/j.1463-1326.2011.01442.x

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