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Article

Single pancreatic beta cells co-express multiple islet hormone genes in mice

22 Oct 2009

Abstract excerpt

AIMS/HYPOTHESIS: It is widely accepted that production of insulin, glucagon, somatostatin and pancreatic polypeptide in islet cells is specific to beta, alpha, delta and pancreatic polypeptide cells, respectively. We examined whether beta cells express other genes encoding islet hormones. METHODS: Nested RT-PCR was performed on single beta cells of transgenic mice with green fluorescent protein (GFP) driven by...

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PMID: 19851748
DOI: 10.1007/s00125-009-1570-x

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