Article
Analysis of the effect of the bovine adenosine triphosphate-binding cassette transporter G2 single nucleotide polymorphism Y581S on transcellular transport of veterinary drugs using new cell culture models.
Journal of animal science - 1 Dec 2011
Real R, González-Lobato L, Baro M F, Valbuena S, de la Fuente A, Prieto J G, Alvarez A I, Marques M M, Merino G
Abstract excerpt
In commercial dairy production, the risk of drug residues and environmental pollutants in milk from ruminants has become an outstanding problem. One of the main determinants of active drug secretion into milk is the ATP-binding cassette transporter G2/breast cancer resistance protein (ABCG2/BCRP)...
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