Article
Evaluation of the association between GHR exon 3 polymorphism and polycystic ovary syndrome among Han Chinese women.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 1 Oct 2011
Shen Yun, Wang Laicheng, Zhao Yueran, You Li, Geng Ling, Gu Harvest F, Chen Zi-Jiang
Abstract excerpt
BACKGROUND: Polycystic ovary syndrome (PCOS) and type 2 diabetes (T2D) are two common metabolic disorders in reproductive-aged women, and both are associated with insulin resistance. Evidence has indicated that the growth hormone receptor (GHR) exon 3 polymorphism is associated with T2D and the GHRd3 allele may have the preventive effect on the disease. However, the genetic effect of this polymorphism on PCOS is...
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