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Article

Polymorphisms and haplotypes of insulin-like factor 3 gene are associated with risk of polycystic ovary syndrome in Indian women.

Gene - 15 Feb 2016

Shaikh Nuzhat, Dadachanji Roshan, Meherji Pervin, Shah Nalini, Mukherjee Srabani

Abstract excerpt

BACKGROUND: Insulin-like factor 3 (INSL3), secreted by the ovarian theca cells is involved in androgen production, follicular growth and oocyte maturation. Both androgens and INSL3 levels are reported to be elevated in women with polycystic ovary syndrome (PCOS), indicating that INSL3 could contribute to PCOS etiology. This case-control association study explored the impact of INSL3 polymorphisms on PCOS...

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Identifiers

PMID: 26625974
DOI: 10.1016/j.gene.2015.11.033

Genes

INSL3
SHBG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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