Article
Family-based analysis of INSR polymorphisms in Chinese PCOS.
Reproductive biomedicine online - 1 Aug 2014
Du Jing, Wang Jianfeng, Sun Xuedong, Xu Xinghua, Zhang Feng, Wang Bin, Shi Yuhua, Chen Zi-jiang
Abstract excerpt
The insulin receptor (INSR), which is an indispensable component of the insulin-signalling pathway, could be a plausible candidate gene for polycystic ovary syndrome (PCOS). This study was designed to determine whether an association exists between three SNP variants (rs3786681, rs17253937 and rs2252673) of the INSR gene and PCOS in Han Chinese. A total of 224 family trios (672 participants in total) were...
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