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Article

Associations of the growth hormone receptor (GHR) gene polymorphisms with adiposity and IGF-I activity in adolescents.

Clinical endocrinology - 1 Sept 2010

Mong Janice L Y, Ng Maggie C Y, Guldan Georgia S, Tam Claudia H T, Lee Heung Man, Ma Ronald C W, So Wing Yee, Wong Gary W K, Kong Alice P S, Chan Juliana C N, Waye Mary M Y

Abstract excerpt

OBJECTIVE: To explore the genetic effect of the GH receptor (GHR) on obesity and related metabolic parameters in Hong Kong Chinese adolescents. CONTEXT: Obesity is a growing global epidemic. Increasing evidence suggests that the GH-IGF-I axis plays an important role in regulating adiposity and insulin sensitivity. DESIGN: We examined the associations of genetic variants of GHR with serum IGF-I and IGFBP-3 levels...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Insulin-Like Growth Factor Binding Protein 3

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Share to Receptors, Somatotropin

Source

Identifiers

PMID: 20105189
DOI: 10.1111/j.1365-2265.2010.03786.x

Genes

GHR

Provenance

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