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Article

Gene expression, chromosome position and lamin A/C mutations.

Nucleus (Austin, Tex.) - 1 Jan 2000

Puckelwartz Megan J, Depreux Frederic Fs, McNally Elizabeth M

Abstract excerpt

The nuclear lamina is increasingly being appreciated for its epigenetic role in regulating gene expression. The nuclear lamina underlies the inner nuclear membrane and, in post mitotic cells, is composed of a latticework primarily formed by the intermediate filament protein, lamin A/C. Although not well defined, lamin-associated domains have been described, and these domains are determined by DNA sequence and...

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Share to Cardiomyopathies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21818408
DOI: 10.4161/nucl.2.3.16003
PMCID: PMC3149875

Genes

LMNA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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