Article

Alteration of epigenetic landscape by lamin A mutations: Hallmark of Dilated Cardiomyopathy

2020-05-01

Abstract excerpt

Mutations in lamin A have been reported to be associated with over 16 human diseases including dilated cardiomyopathy (DCM). We have focused on three such DCM causing mutants of lamin A which have to address the contribution of lamins in the pathogenesis of DCM at molecular level. We have elucidated the effect of these mutants for the first time on the epigenetic landscape of a myogenic fibroblast cell line C2C12....

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Literature Corpus work: f6cfa439-96c3-5b3d-b9b7-cfaec5aa6cf3
DOI: 10.1101/2020.05.01.071803

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