Article
Advances in research on the relationship between the LMNA gene and human diseases (Review).
Molecular medicine reports - 1 Dec 2024
Zhao Jiumei, Zhang Huijuan, Pan Chenglong, He Qian, Zheng Kepu, Tang Yu
Abstract excerpt
The LMNA gene, which is responsible for encoding lamin A/C proteins, is recognized as a primary constituent of the nuclear lamina. This protein serves crucial roles in various cellular physiological activities, including the maintenance of cellular structural stability, regulation of gene expression, mechanosensing and cellular motility. A significant association has been established between the LMNA gene and...
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