Article
Efficient overproduction of membrane proteins in Lactococcus lactis requires the cell envelope stress sensor/regulator couple CesSR.
PloS one - 1 Jan 2011
Pinto Joao P C, Kuipers Oscar P, Marreddy Ravi K R, Poolman Bert, Kok Jan
Abstract excerpt
BACKGROUND: Membrane proteins comprise an important class of molecules whose study is largely frustrated by several intrinsic constraints, such as their hydrophobicity and added requirements for correct folding. Additionally, the complexity of the cellular mechanisms that are required to insert membrane proteins functionally in the membrane and to monitor their folding state makes it difficult to foresee the...
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