Article
Polymorphisms in the neuropeptide Y gene and the risk of obesity: findings from two prospective cohorts.
The Journal of clinical endocrinology and metabolism - 1 Dec 2011
Yeung Edwina H, Zhang Cuilin, Chen Jinbo, Bowers Katherine, Hu Frank B, Kang Guolian, Qi Lu
Abstract excerpt
CONTEXT: Neuropeptide Y (NPY) increases appetite and food intake in animals. Conflicting evidence has been found for the association between polymorphisms of the NPY gene and obesity in humans. OBJECTIVE: The objective of the investigation was to study four single-nucleotide polymorphisms (SNPs) in the NPY gene [rs17149106 (G>T), rs16147 (C>T), rs16139 (T>C), rs5574 (C>T)] with body adiposity. DESIGN: The study...
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