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Article

Global strain engineering by mutant transcription factors.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Lanza Amanda M, Alper Hal S

Abstract excerpt

Cellular hosts are widely used for the production of chemical compounds including pharmaceutics, fuels, and specialty chemicals. Strain engineering focuses on manipulating and improving these hosts for new and enhanced functionalities including increased titers and better bioreactor performance. These tasks have traditionally been accomplished using a combination of random mutation, screening and selection, and...

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PMID: 21815097
DOI: 10.1007/978-1-61779-197-0_15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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