Article
Effect of gene environment interactions on lung function and cardiovascular disease in COPD.
International journal of chronic obstructive pulmonary disease - 1 Jan 2011
Hackett Tillie-Louise, Stefanowicz Dorota, Aminuddin Farzian, Sin Don D, Connett John E, Anthonisen Nicholas R, Paré Peter D, Sandford Andrew J
Abstract excerpt
BACKGROUND: The objective of this study was to determine if gene-environment interactions between cigarette smoking and interleukin-6 (IL6), interferon-γ (IFNG), interleukin-1β (IL1B), or interleukin-1 receptor antagonist (IL1RN) single nucleotide polymorphisms are associated with lung function decline and cardiovascular disease in chronic obstructive pulmonary disease (COPD). METHODS: Single nucleotide...
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