Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modification of the interleukin-6 response to air pollution by interleukin-6 and fibrinogen polymorphisms.

Environmental health perspectives - 1 Sept 2009

Ljungman Petter, Bellander Tom, Schneider Alexandra, Breitner Susanne, Forastiere Francesco, Hampel Regina, Illig Thomas, Jacquemin Bénédicte, Katsouyanni Klea, von Klot Stephanie, Koenig Wolfgang, Lanki Timo, Nyberg Fredrik, Pekkanen Juha, Pistelli Riccardo, Pitsavos Christos, Rosenqvist Mårten, Sunyer Jordi, Peters Annette

Abstract excerpt

BACKGROUND: Evidence suggests that cardiovascular effects of air pollution are mediated by inflammation and that air pollution can induce genetic expression of the interleukin-6 gene (IL6). OBJECTIVES: We investigated whether IL6 and fibrinogen gene variants can affect plasma IL-6 responses to air pollution in patients with cardiovascular disease. METHODS: We repeatedly determined plasma IL-6 in 955 myocardial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Air Pollution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carbon Monoxide

Share to Fibrinogen

Share to FGB gene

Share to Interleukin-6

Share to Myocardial Infarction

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 19750100
DOI: 10.1289/ehp.0800370
PMCID: PMC2737012

Genes

FGB
FGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modification of the interleukin-6 response to air pollution by interleukin-6 and fibrinogen polymorphisms.PMID 19750100Read ↗

Air pollution and inflammatory response in myocardial infarction survivors: gene-environment interactions in a high-risk group.Semantic proximity Read ↗

Interaction between smoking and the interleukin-6 gene affects systemic levels of inflammatory biomarkers.Semantic proximity Read ↗

Fibrinogen genes modify the fibrinogen response to ambient particulate matter.Semantic proximity Read ↗

DNA variants, plasma levels and variability of interleukin-6 in myocardial infarction survivors: results from the AIRGENE study.Semantic proximity Read ↗

Modifying effect of a common polymorphism in the interleukin-6 promoter on the relationship between long-term exposure to traffic-related particulate matter and heart rate variability.Semantic proximity Read ↗

Exposure to Air Pollutants and Myocardial Infarction Incidence: A UK Biobank Study Exploring Gene-Environment Interaction.Semantic proximity Read ↗

Gene-air pollution interaction and cardiovascular disease: a review.Semantic proximity Read ↗

Associations between ambient air pollution and blood markers of inflammation and coagulation/fibrinolysis in susceptible populations.Semantic proximity Read ↗

Effect of gene environment interactions on lung function and cardiovascular disease in COPD.Semantic proximity Read ↗

A common functional variant on the pro-inflammatory Interleukin-6 gene may modify the association between long-term PM10 exposure and diabetes.Semantic proximity Read ↗

Air Pollution and Incident Cardiovascular Disease: Modification by Genetic Susceptibility and the Mitigating Role of Physical Activity.Semantic proximity Read ↗

Co-exposure to multiple air pollutants, genetic susceptibility, and the risk of myocardial infarction onset: a cohort analysis of the UK Biobank participants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.