Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Serum vitamin C and other biomarkers differ by genotype of phase 2 enzyme genes GSTM1 and GSTT1.

The American journal of clinical nutrition - 1 Sept 2011

Block Gladys, Shaikh Nishat, Jensen Christopher D, Volberg Vitaly, Holland Nina

Abstract excerpt

BACKGROUND: Glutathione S-transferases (GSTs) detoxify environmental chemicals and are involved in oxidative stress pathways. Deletion polymorphisms affect enzyme activities and have been associated with risk of disease. OBJECTIVE: The objective was to clarify whether biomarkers of oxidation, antioxidation, inflammation, and nutritional factors differ by GST genotype in healthy adults. DESIGN: Subjects (n = 383)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ascorbic Acid
Share to Biomarkers
Share to Cholesterol

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cholesterol, LDL

Share to Glutathione Transferase

Share to Malondialdehyde

Share to Oxidative Stress

Source

Open in PubMed Open full text

Identifiers

PMID: 21813807
DOI: 10.3945/ajcn.111.011460
PMCID: PMC3155929

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Serum vitamin C and other biomarkers differ by genotype of phase 2 enzyme genes GSTM1 and GSTT1.PMID 21813807Read ↗

Functional genetic variants of glutathione S-transferase protect against serum ascorbic acid deficiency.Semantic proximity Read ↗

GSTM1 and GSTT1 polymorphisms in healthy volunteers - a worldwide systematic review.Semantic proximity Read ↗

Relevance of the deletion polymorphisms of the glutathione S-transferases GSTT1 and GSTM1 in pharmacology and toxicology.Semantic proximity Read ↗

Worldwide Systematic Review of GSTM1 and GSTT1 Null Genotypes by Continent, Ethnicity, and Therapeutic Area.Semantic proximity Read ↗

The Multifaceted Role of Glutathione S-Transferases in Health and DiseaseSemantic proximity Read ↗

Structure, function and disease relevance of Omega-class glutathione transferases.Semantic proximity Read ↗

Diet, glutathione S-transferases M1 and T1 gene polymorphisms and cancer risk: a systematic review of observational studies.Semantic proximity Read ↗

Functional compensation of glutathione S-transferase M1 (GSTM1) null by another GST superfamily member, GSTM2.Semantic proximity Read ↗

Effects of GSTM1/GSTT1 gene polymorphism and fruit & vegetable consumption on antioxidant biomarkers and cognitive function in the elderly: a community based cross-sectional study.Semantic proximity Read ↗

Glutathione S-transferase (GST) M1, but not GSTT1, genotype influences plasma proteomic profiles in Caucasian and East Asian young adults.Semantic proximity Read ↗

Glutathione-S-transferase genotypes, smoking, and their association with markers of inflammation, hemostasis, and endothelial function: the atherosclerosis risk in communities (ARIC) study.Semantic proximity Read ↗

The role of antioxidant gene polymorphisms in modifying the health effects of environmental exposures causing oxidative stress: a public health perspective.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.