Article
Glutathione S-transferase (GST) M1, but not GSTT1, genotype influences plasma proteomic profiles in Caucasian and East Asian young adults.
Journal of proteome research - 5 Oct 2012
Fischer Karina, Da Costa Laura A, García-Bailo Bibiana, Borchers Christoph H, El-Sohemy Ahmed
Abstract excerpt
Glutathione S-transferase (GST) M1 and T1 are major detoxifying enzymes that have been associated with a number of chronic diseases, but their effect on various physiological pathways remains unclear. We investigated the association between the common GSTM1 and GSTT1 genotypes and multiple disease-related high-abundance proteins of the plasma proteome in young Caucasian (n = 476) and East Asian (n = 352) adults....
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