Article
Structure, function and disease relevance of Omega-class glutathione transferases.
Archives of toxicology - 1 May 2016
Board Philip G, Menon Deepthi
Abstract excerpt
The Omega-class cytosolic glutathione transferases (GSTs) have distinct structural and functional attributes that allow them to perform novel roles unrelated to the functions of other GSTs. Mammalian GSTO1-1 has been found to play a previously unappreciated role in the glutathionylation cycle that is emerging as significant mechanism regulating protein function. GSTO1-1-catalyzed glutathionylation or...
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