Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Connexin 37 limits thrombus propensity by downregulating platelet reactivity.

Circulation - 23 Aug 2011

Angelillo-Scherrer Anne, Fontana Pierre, Burnier Laurent, Roth Isabelle, Sugamele Rocco, Brisset Anne, Morel Sandrine, Nolli Séverine, Sutter Esther, Chassot Alexandra, Capron Claude, Borgel Delphine, Saller François, Chanson Marc, Kwak Brenda R

Abstract excerpt

BACKGROUND: Formation of platelet plug initiates hemostasis after vascular injury and triggers thrombosis in ischemic disease. However, the mechanisms leading to the formation of a stable thrombus are poorly understood. Connexins comprise a family of proteins that form gap junctions enabling inte...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Platelet Aggregation
Share to Biotin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Platelets

Share to Connexins

Share to Gap Junctions

Share to Megakaryocytes

Share to Mice, Mutant Strains

Share to Thrombosis

Source

Identifiers

PMID: 21810657
DOI: 10.1161/CIRCULATIONAHA.110.015479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21810657-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Connexin 37 limits thrombus propensity by downregulating platelet reactivity.PMID 21810657Read ↗

Thymidine phosphorylase participates in platelet signaling and promotes thrombosis.Semantic proximity Read ↗

Risky communication in atherosclerosis and thrombus formation.Semantic proximity Read ↗

Overexpression of the platelet P2X1 ion channel in transgenic mice generates a novel prothrombotic phenotype.Semantic proximity Read ↗

Connexin37: a potential modifier gene of inflammatory disease.Semantic proximity Read ↗

Lack of canonical PAR4 activation is associated with reduced arterial and venous thrombosis in miceSemantic proximity Read ↗

Understanding how a highly prevalent GRK5 polymorphism affects platelets and enhances thrombotic risk.Semantic proximity Read ↗

Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice.Semantic proximity Read ↗

Enhanced levels of soluble CD40 ligand exacerbate platelet aggregation and thrombus formation through a CD40-dependent tumor necrosis factor receptor-associated factor-2/Rac1/p38 mitogen-activated protein kinase signaling pathway.Semantic proximity Read ↗

Inhibiting monocyte migration reduces arterial thrombosis and facilitates thrombolysisSemantic proximity Read ↗

Sodium/Potassium ATPase Alpha 1 Subunit Fine-tunes Platelet GPCR Signaling Function and is Essential for ThrombosisSemantic proximity Read ↗

Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation.Semantic proximity Read ↗

Inhibition of the plasma SCUBE1, a novel platelet adhesive protein, protects mice against thrombosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.