Article
The effect of neurogranin on neural correlates of episodic memory encoding and retrieval.
Schizophrenia bulletin - 1 Jan 2013
Krug Axel, Krach Sören, Jansen Andreas, Nieratschker Vanessa, Witt Stephanie H, Shah N Jon, Nöthen Markus M, Rietschel Marcella, Kircher Tilo
Abstract excerpt
Neurogranin (NRGN) is the main postsynaptic protein regulating the availability of calmodulin-Ca(2+) in neurons. NRGN is expressed exclusively in the brain, particularly in dendritic spines and has been implicated in spatial learning and hippocampal plasticity. Genetic variation in rs12807809 in the NRGN gene has recently been confirmed to be associated with schizophrenia in a meta-analysis of genome-wide...
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