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Article

NRG3 contributes to cognitive deficits in chronic patients with schizophrenia.

Schizophrenia research - 1 Jan 2020

Li Zezhi, Liu Lihua, Lin Wei, Zhou Yongjie, Zhang Guangya, Du Xiangdong, Li Yi, Tang Wei, Zhang Xiangyang

Abstract excerpt

BACKGROUND: Cognitive deficit is a fundamental trait of schizophrenia, but its mecwhanisms remain unknown. The neuregulin 3 (NRG3) gene, involving in neuronal function, has been considered to be associated with schizophrenia and cognition. However, no study has investigated the effects of NRG3 polymorphism on cognitive deficits in a large sample of the patients with schizophrenia. METHODS: A total of 1112...

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PMID: 31753594
DOI: 10.1016/j.schres.2019.10.060

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