Article
Investigation of the association between dopamine D1 receptor gene polymorphisms and essential hypertension in a group of Turkish subjects.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2011
Orun Oya, Nacar Cevdet, Cabadak Hülya, Tiber Pınar Mega, Doğan Yüksel, Güneysel Özlem, Fak Ali Serdar, Kan Beki
Abstract excerpt
Dopamine has been shown to influence blood pressure by regulating renal sodium excretion through direct interaction with the dopamine receptors, especially with the Dopamine D1 receptor (DRD1). To better understand the role of polymorphisms in those effects, we investigated the association between two polymorphic sites in the DRD1 promoter region (A-48G, G-94A) and essential hypertension in the Turkish...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.