Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dopamine D1 receptor gene polymorphism is associated with essential hypertension.

Hypertension (Dallas, Tex. : 1979) - 1 Aug 2000

Sato M, Soma M, Nakayama T, Kanmatsuse K

Abstract excerpt

Dopamine has been shown to influence renal sodium excretion through a direct interaction with the dopamine receptor (DR). The dopamine D1 receptor (DRD1) has been localized to the proximal tubules and is known to increase sodium excretion by inhibiting Na-H exchanger and Na,K-ATPase activity. Defective renal dopamine production and/or DR function have been reported in essential hypertension (EH) as well as in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Blood Pressure
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diastole

Share to Hypertension

Share to Polymorphism, Restriction Fragment Length

Share to Receptors, Dopamine D1

Share to Systole

Source

Identifiers

PMID: 10948075
DOI: 10.1161/01.hyp.36.2.183

Genes

DRD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dopamine D1 receptor gene polymorphism is associated with essential hypertension.PMID 10948075Read ↗

Investigation of the association between dopamine D1 receptor gene polymorphisms and essential hypertension in a group of Turkish subjects.Semantic proximity Read ↗

Association of Dopamine D1 and D3 Receptor Gene Polymorphisms with Essential Hypertension in 3 Ethnic Groups in China.Semantic proximity Read ↗

Ethnic origin determines the impact of genetic variants in dopamine receptor gene (DRD1) concerning essential hypertension.Semantic proximity Read ↗

Dopamine D1 receptor (DRD1) genetic polymorphism: pleiotropic effects on heritable renal traits.Semantic proximity Read ↗

Ser9Gly polymorphism in the dopamine D3 receptor gene is not associated with essential hypertension in the Japanese.Semantic proximity Read ↗

Functional genomics of the dopaminergic system in hypertensionSemantic proximity Read ↗

Reactive oxygen species and dopamine receptor function in essential hypertension.Semantic proximity Read ↗

Investigation of the correlation between norepinephrine transporter gene polymorphisms and essential hypertension.Semantic proximity Read ↗

Blood pressure and renal sodium handling in relation to genetic variation in the DRD1 promoter and GRK4.Semantic proximity Read ↗

G protein-coupled receptor kinase 4 gene variants in human essential hypertension.Semantic proximity Read ↗

Molecular characterization, expression profile, and polymorphism of goose dopamine D1 receptor gene.Semantic proximity Read ↗

[Relationship between dopamine D4 receptor gene polymorphisms and primary nocturnal enuresis].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.