Article
Ethnic origin determines the impact of genetic variants in dopamine receptor gene (DRD1) concerning essential hypertension.
American journal of hypertension - 1 Dec 2004
Beige Joachim, Bellmann Astrid, Sharma Arya M, Gessner Reinhard
Abstract excerpt
The dopamine receptor type 1 (DRD1) has been implicated in the development of hypertension in humans as well as in animal models of spontaneous hypertension. We screened the entire coding and promoter region of the human DRD1 receptor for polymorphisms to analyze their association with hypertension. The allele frequencies of two common single-nucleotide polymorphisms, A-48G and G-94A were determined in 493...
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