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Article

Association between a functional dopamine D4 receptor promoter region polymorphism (-C521T) and pre-eclampsia: a family-based study.

Molecular human reproduction - 1 Feb 2006

Korobochka Roman, Gritsenko Inga, Gonen Ron, Ebstein Richard P, Ohel Gonen

Abstract excerpt

Although many candidate genes have been studied in pre-eclampsia (PE), the important class of catecholamine receptors that contribute to sympathetic tone and blood pressure regulation has yet to be investigated. We therefore examined the dopamine D4 receptor (DRD4) gene. We performed a prospective family-based study in 50 families (patient and both her parents) who were genotyped for three DRD4 promoter regions....

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Share to DRD4 gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Polymorphism, Single Nucleotide

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Share to Promoter Regions, Genetic

Share to Receptors, Dopamine D4

Source

Identifiers

PMID: 16455620
DOI: 10.1093/molehr/gal004

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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