Article
A48G polymorphism in the D1 receptor genes associated with bipolar I disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2005
Severino Giovanni, Congiu Donatella, Serreli Claudia, De Lisa Roberto, Chillotti Caterina, Del Zompo Maria, Piccardi Maria Paola
Abstract excerpt
Several lines of evidence point to a role for dopamine in mood disorders and, in particular, in bipolar disorders. In line with a considerable amount of evidence, the dopamine D1 receptor gene (DRD1) is considered to be a good candidate gene for bipolar disorders. Several studies did not find any association between bipolar 1 patients and DRD1. In this study, we investigate a possible association between BP...
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