Article
Validation of a tentative microsatellite marker for the dopamine D4 receptor gene by capillary gel electrophoresis.
Journal of chromatography. A - 20 Oct 2006
Toth-Petroczy Agnes, Szilagyi Agnes, Ronai Zsolt, Sasvari-Szekely Maria, Guttman András
Abstract excerpt
Two to four-basepair-short tandem repeats (i.e. microsatellites) are broadly utilized as genetic markers for mapping disease loci in whole genome search analyses. Based on their close vicinity on chromosome 11, the D11S1984 microsatellite was anticipated as a tentative marker for the dopamine D4 receptor gene. A capillary gel electrophoresis based genotype analysis method and an in-house made computational tool...
Topics
- Electrophoresis, Capillary
- Genotype
- Humans
- Microsatellite Repeats
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Receptors, Dopamine D4
- Reproducibility of Results
