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Article

Growing backwards: an inverted role for the shrimp ortholog of vertebrate myostatin and GDF11.

The Journal of experimental biology - 15 Aug 2011

De Santis Christian, Wade Nicholas M, Jerry Dean R, Preston Nigel P, Glencross Brett D, Sellars Melony J

Abstract excerpt

Myostatin (MSTN) and growth differentiation factor-11 (GDF11) are closely related proteins involved in muscle cell growth and differentiation as well as neurogenesis of vertebrates. Both MSTN and GDF11 negatively regulate their functions. Invertebrates possess a single ortholog of the MSTN/GDF11 family. In order to understand the role of MSTN/GDF11 in crustaceans, the gene ortholog was identified and...

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Source

Identifiers

PMID: 21795562
DOI: 10.1242/jeb.056374

Genes

GDF11
MSTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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