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GDF11 and aging biology - controversies resolved and pending

18 Oct 2023

Abstract excerpt

Since the exogenous administration of GDF11, a TGF-ß superfamily member, was reported to have beneficial effects in some models of human disease, there have been many research studies in GDF11 biology. However, many studies have now confirmed that exogenous administration of GDF11 can improve physiology in disease models, including cardiac fibrosis, experimental stroke, and disordered metabolism. GDF11 is similar...

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PMID: 38235060
DOI: 10.20517/jca.2023.23

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