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Article

Association of the Pro12Ala and C1431T variants of PPARgamma and their haplotypes with susceptibility to gestational diabetes.

The Journal of clinical endocrinology and metabolism - 1 Oct 2011

Heude Barbara, Pelloux Veronique, Forhan Anne, Bedel Jean-François, Lacorte Jean-Marc, Clément Karine, Charles Marie-Aline

Abstract excerpt

BACKGROUND: The protective role of the Ala allele in the Pro12Ala polymorphism of PPARγ on type 2 diabetes has been well established but not confirmed in the context of pregnancy, for gestational diabetes, a known predictor of later type 2 diabetes onset. Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with Pro12Ala and has been shown to be associated with body weight, but its...

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Identifiers

PMID: 21795447
DOI: 10.1210/jc.2011-0381

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Association of the Pro12Ala and C1431T variants of PPARgamma and their haplotypes with susceptibility to gestational diabetes.PMID 21795447Read ↗

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