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Article

Association of PPARγ2Pro12Ala polymorphism with gestational diabetes mellitus risk: A systematic review and meta-analysis.

Biomolecules & biomedicine - 18 Nov 2025

Xu Yuanting, Du Yi, Shan Tengfei, Xie Qingwen, Zhu Hongli

Abstract excerpt

Gestational diabetes mellitus (GDM) is a prevalent pregnancy complication that poses significant risks to both mothers and their offspring, with genetic susceptibility believed to play a role in its pathogenesis. This study examined the association between the Pro12Ala (Pro [C]→Ala [G]) polymorphism in the peroxisome proliferator-activated receptor γ2 (PPARγ2) gene and the risk of developing GDM. A systematic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41251318
DOI: 10.17305/bb.2025.13079
PMCID: PMC12834310

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