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Article

Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on plasma lipids and diabetes risk in an Asian population.

Journal of lipid research - 1 Apr 2004

Tai E Shyong, Corella Dolores, Deurenberg-Yap Mabel, Adiconis Xian, Chew Suok Kai, Tan Chee Eng, Ordovas Jose M

Abstract excerpt

We investigated the association of C1431T and Pro12Ala polymorphisms at the peroxisome proliferator-activated receptor gamma (PPARgamma) locus with plasma lipids and insulin resistance-related variables, according to diabetes status, in a large and representative Asian population from Singapore consisting of 2,730 Chinese, 740 Malays, and 568 Indians. Moreover, we estimated the diabetes risk and examined...

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Identifiers

PMID: 14729856
DOI: 10.1194/jlr.M300363-JLR200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on plasma lipids and diabetes risk in an Asian population.PMID 14729856Read ↗

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Peroxisome proliferator‑activated receptor γ polymorphisms as risk factors for dyslipidemia.Semantic proximity Read ↗

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[Association of the Pro12Ala and C1431T polymorphism of the PPAR gamma2 gene and their haplotypes with obesity and type 2 diabetes].Semantic proximity Read ↗

Association of the Pro12Ala and C1431T variants of PPARG and their haplotypes with susceptibility to Type 2 diabetes.Semantic proximity Read ↗

Association of the variants in the PPARG gene and serum lipid levels: a meta-analysis of 74 studies.Semantic proximity Read ↗

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The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over 6 years and combines with the effect of the APM1 G-11391A single nucleotide polymorphism: the Data From an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) study.Semantic proximity Read ↗

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