Article
A common matrix metalloproteinase (MMP)-2 polymorphism affects plasma MMP-2 levels in subjects environmentally exposed to mercury.
The Science of the total environment - 15 Sept 2011
Jacob-Ferreira Anna L B, Lacchini Riccardo, Gerlach Raquel F, Passos Carlos J S, Barbosa Fernando, Tanus-Santos Jose E
Abstract excerpt
Mercury (Hg) exposure is associated with disease conditions, including cardiovascular problems. Although the mechanisms implicated in these complications have not been precisely defined yet, matrix metalloproteinases (MMPs) may be involved. The gene encoding MMP-2 presents genetic polymorphisms which affect the expression and activity level of this enzyme. A common polymorphism of MMP-2 gene is the C(-1306)T (rs...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.