Article
The association of the blood lead level and serum lipid concentrations may be modified by the genetic combination of the metallothionein 2A polymorphisms rs10636 GC and rs28366003 AA.
Journal of clinical lipidology - 1 Jan 2000
Yang Chen-Cheng, Chuang Chih-Shien, Lin Chia-I, Wang Chao-Ling, Huang Yung-Cheng, Chuang Hung-Yi
Abstract excerpt
BACKGROUND: Lead in blood can stimulate lipid oxidation in phosphatidylcholine and increase peroxidation in lipids. Metallothionein (MT) is a cysteine-rich protein that can influence the detoxification of heavy metals and scavenge oxidative stress for free radicals. One of the most expressive functional genes in humans is the MT2A gene. OBJECTIVE: This study aims to determine if the association of the blood lead...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.