Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Smooth muscle phenotypic diversity is mediated through alterations in myocardin gene splicing.

Journal of cellular physiology - 1 Oct 2011

Ilagan Roger M, Genheimer Christopher W, Quinlan Sarah F, Guthrie Kelly I, Sangha Namrata, Ramachandrannair Sajini, Kelley Rusty W, Presnell Sharon C, Basu Joydeep, Ludlow John W

Abstract excerpt

Myocardin (MYOCD) is a smooth and cardiac muscle-specific transcriptional coactivator that is required for the proper expression of contraction-related genes. Through its function to transactivate effector genes, MYOCD plays an essential role in mediating the switch between contractile and non-contractile phenotypes, particularly in smooth muscle cells (SMC). There are at least two known transcript variants of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Aorta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carotid Arteries

Share to Conserved Sequence

Share to In Vitro Techniques

Share to Myocytes, Smooth Muscle

Share to Trans-Activators

Share to Urinary Bladder

Source

Identifiers

PMID: 21792927
DOI: 10.1002/jcp.22622

Genes

MYOCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Smooth muscle phenotypic diversity is mediated through alterations in myocardin gene splicing.PMID 21792927Read ↗

The Smooth Muscle Cell-restricted KCNMB1 Ion Channel Subunit Is a Direct Transcriptional Target of Serum Response Factor and MyocardinSemantic proximity Read ↗

Myocardin in biology and diseaseSemantic proximity Read ↗

Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice.Semantic proximity Read ↗

SMYD2 Regulates Vascular Smooth Muscle Cell Phenotypic Switching and Intimal Hyperplasia via Interaction with MyocardinSemantic proximity Read ↗

Transcriptional control of a novel long noncoding RNA Mymsl in smooth muscle cells by a single Cis-element and its initial functional characterization in vessels.Semantic proximity Read ↗

Myocardin is required for maintenance of vascular and visceral smooth muscle homeostasis during postnatal development.Semantic proximity Read ↗

Myocardin: A novel player in atherosclerosis.Semantic proximity Read ↗

The serum response factor coactivator myocardin is required for vascular smooth muscle development.Semantic proximity Read ↗

Myocardin-dependent Activation of the CArG Box-rich Smooth Muscle γ-Actin GeneSemantic proximity Read ↗

Discovery of Transacting Long Noncoding RNAs That Regulate Smooth Muscle Cell Phenotype.Semantic proximity Read ↗

Myocardin overexpression is sufficient for promoting the development of a mature smooth muscle cell-like phenotype from human embryonic stem cells.Semantic proximity Read ↗

Leiomodin 1, a New Serum Response Factor-dependent Target Gene Expressed Preferentially in Differentiated Smooth Muscle CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.