Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PRL‑3 increases the aggressive phenotype of prostate cancer cells in vitro and its expression correlates with high-grade prostate tumors in patients.

International journal of oncology - 1 Feb 2018

Edwards Donna R, Moroz Krzysztof, Zhang Haitao, Mulholland David, Abdel-Mageed Asim B, Mondal Debasis

Abstract excerpt

The increased expression of phosphatase of regenerating liver-3 (PRL‑3) has been shown to be associated with the aggressive and metastatic phenotype of different solid tumors. However, it is not known whether PRL‑3 plays a similar role in the progression of prostate cancer (PCa). In this study, immunoblot analysis of androgen receptor (AR)-positive PCa lines (LNCaP and LNCaP‑SF) revealed the constitutive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Neoplasm Grading

Share to Neoplasm Proteins

Share to Neoplasm Staging

Share to Prostatic Neoplasms

Share to Protein Tyrosine Phosphatases

Source

Open in PubMed Open full text

Identifiers

PMID: 29207031
DOI: 10.3892/ijo.2017.4208
PMCID: PMC5741371

Genes

PRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PRL‑3 increases the aggressive phenotype of prostate cancer cells in vitro and its expression correlates with high-grade prostate tumors in patients.PMID 29207031Read ↗

Relationship of Common Variants in PRL-3 Gene With Susceptibility and Prognosis of Prostate CancerSemantic proximity Read ↗

PRL phosphatases as potential molecular targets in cancerSemantic proximity Read ↗

Unique patterns of molecular profiling between human prostate cancer LNCaP and PC‐3 cellsSemantic proximity Read ↗

PBX3 is a putative biomarker of aggressive prostate cancerSemantic proximity Read ↗

A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses.Semantic proximity Read ↗

Characterization of a Prostate- and Prostate Cancer-Specific Circular RNA Encoded by the Androgen Receptor GeneSemantic proximity Read ↗

Phosphatase of regenerating liver: a novel target for cancer therapySemantic proximity Read ↗

Phosphatase of regenerating liver-3 inhibits invasiveness and proliferation in non-small cell lung cancer by regulating the epithelial-mesenchymal transition.Semantic proximity Read ↗

Metastasis-associated phosphatase PRL-2 regulates tumor cell migration and invasion.Semantic proximity Read ↗

Use of multiple biomarkers for a molecular diagnosis of prostate cancerSemantic proximity Read ↗

Intratumoral LAG-3 + cells infiltration determines poor prognosis in patients with castration-naïve prostate cancerSemantic proximity Read ↗

Differential expression of peroxiredoxins in prostate cancer: Consistent upregulation of PRDX3 and PRDX4Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.