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Article

Divergent human populations show extensive shared IGK rearrangements in peripheral blood B cells.

Immunogenetics - 1 Jan 2012

Jackson Katherine Jean Louise, Wang Yan, Gaeta Bruno A, Pomat William, Siba Peter, Rimmer Janet, Sewell William A, Collins Andrew M

Abstract excerpt

We have analysed the transcribed immunoglobulin kappa (IGK) repertoire of peripheral blood B cells from four individuals from two genetically distinct populations, Papua New Guinean and Australian, using high-throughput DNA sequencing. The depth of sequencing data for each individual averaged 5,548 high-quality IGK reads, and permitted genotyping of the inferred IGKV and IGKJ germline gene segments for each...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21789596
DOI: 10.1007/s00251-011-0559-z

Genes

IGK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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