Article
Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: Relevance in infectious diseases and vaccination studies in human populations.
Genes and immunity - 1 Jul 2021
Khatri Indu, Berkowska Magdalena A, van den Akker Erik B, Teodosio Cristina, Reinders Marcel J T, van Dongen Jacques J M
Abstract excerpt
Immunoglobulin (IG) loci harbor inter-individual allelic variants in many different germline IG variable, diversity and joining genes of the IG heavy (IGH), kappa (IGK) and lambda (IGL) loci, which together form the genetic basis of the highly diverse antigen-specific B-cell receptors. These allelic variants can be shared between or be specific to human populations. The current immunogenetics resources gather the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
