Article
Ovarian cancer stem cells: still an elusive entity?
Molecular cancer - 20 Mar 2017
Lupia Michela, Cavallaro Ugo
Abstract excerpt
The cancer stem cell (CSC) model proposes that tumor development and progression are fueled and sustained by undifferentiated cancer cells, endowed with self-renewal and tumor-initiating capacity. Ovarian carcinoma, based on its biological features and clinical evolution, appears as a prototypical example of CSC-driven disease. Indeed, ovarian cancer stem cells (OCSC) would account not only for the primary tumor...
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