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Article

Predicting the response to combination antiretroviral therapy: retrospective validation of geno2pheno-THEO on a large clinical database.

The Journal of infectious diseases - 1 Apr 2009

Altmann André, Däumer Martin, Beerenwinkel Niko, Peres Yardena, Schülter Eugen, Büch Joachim, Rhee Soo-Yon, Sönnerborg Anders, Fessel W Jeffrey, Shafer Robert W, Zazzi Maurizio, Kaiser Rolf, Lengauer Thomas

Abstract excerpt

BACKGROUND: Expert-based genotypic interpretation systems are standard methods for guiding treatment selection for patients infected with human immunodeficiency virus type 1. We previously introduced the software pipeline geno2pheno-THEO (g2p-THEO), which on the basis of viral sequence predicts the response to treatment with a combination of antiretroviral compounds by applying methods from statistical learning...

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PMID: 19239365
DOI: 10.1086/597305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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