Article
Collaborative update of a rule-based expert system for HIV-1 genotypic resistance test interpretation.
PloS one - 1 Jan 2017
Paredes Roger, Tzou Philip L, van Zyl Gert, Barrow Geoff, Camacho Ricardo, Carmona Sergio, Grant Philip M, Gupta Ravindra K, Hamers Raph L, Harrigan P Richard, Jordan Michael R, Kantor Rami, Katzenstein David A, Kuritzkes Daniel R, Maldarelli Frank, Otelea Dan, Wallis Carole L, Schapiro Jonathan M, Shafer Robert W
Abstract excerpt
INTRODUCTION: HIV-1 genotypic resistance test (GRT) interpretation systems (IS) require updates as new studies on HIV-1 drug resistance are published and as treatment guidelines evolve. METHODS: An expert panel was created to provide recommendations for the update of the Stanford HIV Drug Resistance Database (HIVDB) GRT-IS. The panel was polled on the ARVs to be included in a GRT report, and the drug-resistance...
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