Article
2021 update to HIV-TRePS: a highly flexible and accurate system for the prediction of treatment response from incomplete baseline information in different healthcare settings.
The Journal of antimicrobial chemotherapy - 18 Jun 2021
Revell Andrew D, Wang Dechao, Perez-Elias Maria-Jesus, Wood Robin, Cogill Dolphina, Tempelman Hugo, Hamers Raph L, Reiss Peter, van Sighem Ard, Rehm Catherine A, Agan Brian, Alvarez-Uria Gerardo, Montaner Julio S G, Lane H Clifford, Larder Brendan A
Abstract excerpt
OBJECTIVES: With the goal of facilitating the use of HIV-TRePS to optimize therapy in settings with limited healthcare resources, we aimed to develop computational models to predict treatment responses accurately in the absence of commonly used baseline data. METHODS: Twelve sets of random forest models were trained using very large, global datasets to predict either the probability of virological response...
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