Article
A comparison of three computational modelling methods for the prediction of virological response to combination HIV therapy.
Artificial intelligence in medicine - 1 Sept 2009
Wang Dechao, Larder Brendan, Revell Andrew, Montaner Julio, Harrigan Richard, De Wolf Frank, Lange Joep, Wegner Scott, Ruiz Lidia, Pérez-Elías María Jésus, Emery Sean, Gatell Jose, D'Arminio Monforte Antonella, Torti Carlo, Zazzi Maurizio, Lane Clifford
Abstract excerpt
OBJECTIVE: HIV treatment failure is commonly associated with drug resistance and the selection of a new regimen is often guided by genotypic resistance testing. The interpretation of complex genotypic data poses a major challenge. We have developed artificial neural network (ANN) models that predict virological response to therapy from HIV genotype and other clinical information. Here we compare the accuracy of...
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