Article
A comparison of computational models with and without genotyping for prediction of response to second-line HIV therapy.
HIV medicine - 1 Aug 2014
Revell A D, Boyd M A, Wang D, Emery S, Gazzard B, Reiss P, van Sighem A I, Montaner J S, Lane H C, Larder B A
Abstract excerpt
OBJECTIVES: We compared the use of computational models developed with and without HIV genotype vs. genotyping itself to predict effective regimens for patients experiencing first-line virological failure. METHODS: Two sets of models predicted virological response for 99 three-drug regimens for patients on a failing regimen of two nucleoside/nucleotide reverse transcriptase inhibitors and one nonnucleoside...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.