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Article

Insertional inactivation of the mec gene in a transposon mutant of a methicillin-resistant clinical isolate of Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 Sept 1990

Matthews P, Tomasz A

Abstract excerpt

All clinical strains of methicillin-resistant Staphylococcus aureus (MRSA) examined so far contain the mec gene and its product, the penicillin-binding protein (PBP) 2A. Yet the same strains show tremendous variation in the phenotypic expression of antibiotic resistance (MIC), which is under the...

Topics

Blotting, Southern
DNA Transposable Elements
Gene Expression Regulation, Bacterial
Methicillin
Methicillin Resistance
Microbial Sensitivity Tests
Mutation
Nucleic Acid Hybridization
Staphylococcus aureus

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2178337
DOI: 10.1128/AAC.34.9.1777
PMCID: PMC171923

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2178337-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Insertional inactivation of the mec gene in a transposon mutant of a methicillin-resistant clinical isolate of Staphylococcus aureus.PMID 2178337Read ↗

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