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Article

Strong synergy between mutant ras and HPV16 E6/E7 in the development of primary tumors.

Oncogene - 13 May 2004

Schreiber Karin, Cannon Ronald E, Karrison Theodore, Beck-Engeser Gabriele, Huo Dezheng, Tennant Raymond W, Jensen Heather, Kast W Martin, Krausz Thomas, Meredith Stephen C, Chen Lieping, Schreiber Hans

Abstract excerpt

E6/E7 oncogenes of high-risk human papilloma virus (HPV) subtypes are essential for the development of certain types of cancers. However, these oncogenes are insufficient to transform normal cells into an immortalized or malignant state. Mutant Ha-ras cooperates with E6/E7 of HPV subtype 16 in tr...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15077191
DOI: 10.1038/sj.onc.1207507

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15077191-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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