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Article

Basal-Like Breast Cancer: A Critical Review

16 May 2008

Abstract excerpt

Recent gene expression profiling of breast cancer has identified specific subtypes with clinical, biologic, and therapeutic implications. The basal-like group of tumors is characterized by an expression signature similar to that of the basal/myoepithelial cells of the breast and is reported to have transcriptomic characteristics similar to those of tumors arising in BRCA1 germline mutation carriers. They are...

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PMID: 18487574
DOI: 10.1200/jco.2007.13.1748

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