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Minireview: Basal-Like Breast Cancer: From Molecular Profiles to Targeted Therapies

23 Sept 2010

Abstract excerpt

The classification of breast cancer into molecular subtypes with distinctive gene expression signatures that predict treatment response and prognosis has ushered in a new era of personalized medicine for this remarkably heterogeneous and deadly disease. Basal-like breast cancer (BLBC) is a particularly aggressive molecular subtype defined by a robust cluster of genes expressed by epithelial cells in the basal or...

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PMID: 20861225
DOI: 10.1210/me.2010-0164

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